Faculty Profiles

Carmen Peralta, MD
MED-CAMPUS-NEPHROLOGY
Assistant Professor in Residence

Core Campus, HSE
415-476-2173
carmenalicia.peralta@ucsf.edu

EDUCATION
College: Rice University, BA
Medical School: Johns Hopkins University School of Medicine, MD
Other Graduate Training: University of California, San Francisco, MAS
Internal Medicine Residency: Brigham and Women's Hospital
Nephrology Fellowship: University of California, San Francisco

Dr. Peralta is Assistant Professor in Residence based at UCSF Moffit-Long and the San Francisco VA Medical Center. Her research activities focus on three major areas: (1) Translational approaches to understanding mechanisms for racial/ethnic disparities in kidney disease; (2) Hypertension, arterial stiffness and kidney disease; and (3) Novel biomarkers for detection, classification and risk stratification for early kidney disease in diverse populations.

Dr. Peralta has established translational collaborations with a multi-disciplinary team of investigators in nephrology, general internal medicine, epidemiology, and human genetics both at UCSF and around the country. She is an active member of the renal working groups in several major ongoing cohort studies that include The Multi-Ethnic Study of Atherosclerosis (MESA), the Cardiovascular Health Study (CHS) and the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Dr. Peralta is also a member of the national steering committee for research of the Kidney Early Evaluation Program (KEEP) from the National Kidney Foundation.

Dr. Peralta's work is funded by a K23 Award from the National Insitutes of Health (NIDDK) and a Harold Amos Faculty Development Award from the Robert Wood Johnson Foundation.

Recent Articles (57)

Peralta CA, Weekley CC, Li Y, Shlipak MG. Occult chronic kidney disease among persons with hypertension in the United States: data from the national health and nutrition surveys 1988-1994 and 1999-2002. J Hypertens. 2013 Jun; 31(6):1196-202.

Zeki Al Hazzouri A, Haan MN, Neuhaus JM, Pletcher M, Peralta CA, López L, Pérez Stable EJ. Cardiovascular risk score, cognitive decline, and dementia in older mexican americans: the role of sex and education. J Am Heart Assoc. 2013; 2(2):e004978.

Chang TI, Li S, Chen SC, Peralta CA, Shlipak MG, Fried LF, Whaley-Connell AT, McCullough PA, Kurella Tamura M. Risk Factors for ESRD in Individuals With Preserved Estimated GFR With and Without Albuminuria: Results From the Kidney Early Evaluation Program (KEEP). Am J Kidney Dis. 2013 Apr; 61(4 Suppl 2):S4-S11.

Odden MC, Peralta CA, Covinsky KE. Walking speed is a useful marker of frailty in older persons-reply. JAMA Intern Med. 2013 Feb 25; 173(4):325-6.

Madero M, Peralta C, Katz R, Canada R, Fried L, Najjar S, Shlipak M, Simonsick E, Lakatta E, Patel K, Rifkin D, Hawkins M, Newman A, Sarnak M. Association of Arterial Rigidity with Incident Kidney Disease and Kidney Function Decline: The Health ABC Study. Clin J Am Soc Nephrol. 2013 Mar; 8(3):424-33.

Peralta CA, Lee A, C Odden M, Lopez L, Zeki Al Hazzouri A, Neuhaus J, Haan MN. Association between chronic kidney disease detected using creatinine and cystatin C and death and cardiovascular events in elderly mexican americans: the sacramento area latino study on aging. J Am Geriatr Soc. 2013 Jan; 61(1):90-5.

Shlipak MG, Scherzer R, Abraham A, Tien PC, Grunfeld C, Peralta CA, Devarajan P, Bennett M, Butch AW, Anastos K, Cohen MH, Nowicki M, Sharma A, Young MA, Sarnak MJ, Parikh CR. Urinary markers of kidney injury and kidney function decline in HIV-infected women. J Acquir Immune Defic Syndr. 2012 Dec 15; 61(5):565-73.

Peralta CA. Bucking conventional wisdom and focusing on disparities to address kidney disease. Health Aff (Millwood). 2012 Dec; 31(12):2797-8.

Odden MC, Peralta CA, Haan MN, Covinsky KE. Rethinking the association of high blood pressure with mortality in elderly adults: the impact of frailty. Arch Intern Med. 2012 Aug 13; 172(15):1162-8.

Peralta CA, Katz R, Bonventre JV, Sabbisetti V, Siscovick D, Sarnak M, Shlipak MG. Associations of Urinary Levels of Kidney Injury Molecule 1 (KIM-1) and Neutrophil Gelatinase-Associated Lipocalin (NGAL) With Kidney Function Decline in the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Kidney Dis. 2012 Dec; 60(6):904-11.

Shastri S, Katz R, Rifkin DE, Fried LF, Odden MC, Peralta CA, Chonchol M, Siscovick D, Shlipak MG, Newman AB, Sarnak MJ. Kidney function and mortality in octogenarians: Cardiovascular Health Study All Stars. J Am Geriatr Soc. 2012 Jul; 60(7):1201-7.

Park M, Shlipak MG, Katz R, Agarwal S, Ix JH, Hsu CY, Peralta CA. Subclinical cardiac abnormalities and kidney function decline: the multi-ethnic study of atherosclerosis. Clin J Am Soc Nephrol. 2012 Jul; 7(7):1137-44.

Hiramoto JS, Katz R, Peralta CA, Ix JH, Fried L, Cushman M, Siscovick D, Palmas W, Sarnak M, Shlipak MG. Inflammation and coagulation markers and kidney function decline: the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Kidney Dis. 2012 Aug; 60(2):225-32.

Manichaikul A, Palmas W, Rodriguez CJ, Peralta CA, Divers J, Guo X, Chen WM, Wong Q, Williams K, Kerr KF, Taylor KD, Tsai MY, Goodarzi MO, Sale MM, Diez-Roux AV, Rich SS, Rotter JI, Mychaleckyj JC. Population structure of Hispanics in the United States: the multi-ethnic study of atherosclerosis. PLoS Genet. 2012; 8(4):e1002640.

de Boer IH, Katz R, Chonchol MB, Fried LF, Ix JH, Kestenbaum B, Mukamal KJ, Peralta CA, Siscovick DS. Insulin resistance, cystatin C, and mortality among older adults. Diabetes Care. 2012 Jun; 35(6):1355-60.

Odden MC, Covinsky KE, Neuhaus JM, Mayeda ER, Peralta CA, Haan MN. The association of blood pressure and mortality differs by self-reported walking speed in older Latinos. J Gerontol A Biol Sci Med Sci. 2012 Sep; 67(9):977-83.

Ix JH, Katz R, de Boer IH, Kestenbaum BR, Peralta CA, Jenny NS, Budoff M, Allison MA, Criqui MH, Siscovick D, Shlipak MG. Fetuin-A is inversely associated with coronary artery calcification in community-living persons: the Multi-Ethnic Study of Atherosclerosis. Clin Chem. 2012 May; 58(5):887-95.

Dubin R, Li Y, Ix JH, Shlipak MG, Whooley M, Peralta CA. Associations of pentraxin-3 with cardiovascular events, incident heart failure, and mortality among persons with coronary heart disease: data from the Heart and Soul Study. Am Heart J. 2012 Feb; 163(2):274-9.

Peralta CA, Norris KC, Li S, Chang TI, Tamura MK, Jolly SE, Bakris G, McCullough PA, Shlipak M. Blood pressure components and end-stage renal disease in persons with chronic kidney disease: the Kidney Early Evaluation Program (KEEP). Arch Intern Med. 2012 Jan 9; 172(1):41-7.

Gutiérrez OM, Katz R, Peralta CA, de Boer IH, Siscovick D, Wolf M, Diez Roux A, Kestenbaum B, Nettleton JA, Ix JH. Associations of socioeconomic status and processed food intake with serum phosphorus concentration in community-living adults: the Multi-Ethnic Study of Atherosclerosis (MESA). J Ren Nutr. 2012 Sep; 22(5):480-9.

Rodriguez F, Peralta CA, Green AR, López L. Comparison of C-reactive protein levels in less versus more acculturated Hispanic adults in the United States (from the National Health and Nutrition Examination Survey 1999-2008). Am J Cardiol. 2012 Mar 1; 109(5):665-9.

Muntner P, Newsome B, Kramer H, Peralta CA, Kim Y, Jacobs DR, Kiefe CI, Lewis CE. Racial differences in the incidence of chronic kidney disease. Clin J Am Soc Nephrol. 2012 Jan; 7(1):101-7.

Peralta CA, Katz R, Shlipak M, Dubin R, DeBoer I, Jenny N, Fitzpatrick A, Koro C, Kestenbaum B, Ix J, Sarnak M, Cushman M. Kidney function decline in the elderly: impact of lipoprotein-associated phospholipase A(2). Am J Nephrol. 2011; 34(6):512-8.

Peralta CA, Jacobs DR, Katz R, Ix JH, Madero M, Duprez DA, Sarnak MJ, Criqui MH, Kramer HJ, Palmas W, Herrington D, Shlipak MG. Association of pulse pressure, arterial elasticity, and endothelial function with kidney function decline among adults with estimated GFR >60 mL/min/1.73 m(2): the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Kidney Dis. 2012 Jan; 59(1):41-9.

Odden MC, Tager IB, van der Laan MJ, Delaney JA, Peralta CA, Katz R, Sarnak MJ, Psaty BM, Shlipak MG. Antihypertensive medication use and change in kidney function in elderly adults: a marginal structural model analysis. Int J Biostat. 2011; 7(1):Article 34.

Liu CT, Garnaas MK, Tin A, Kottgen A, Franceschini N, Peralta CA, de Boer IH, Lu X, Atkinson E, Ding J, Nalls M, Shriner D, Coresh J, Kutlar A, Bibbins-Domingo K, Siscovick D, Akylbekova E, Wyatt S, Astor B, Mychaleckjy J, Li M, Reilly MP, Townsend RR, Adeyemo A, Zonderman AB, de Andrade M, Turner ST, Mosley TH, Harris TB. Genetic association for renal traits among participants of African ancestry reveals new loci for renal function. PLoS Genet. 2011 Sep; 7(9):e1002264.

Wassel CL, Jacobs DR, Duprez DA, Bluemke DA, Sibley CT, Criqui MH, Peralta CA. Association of self-reported race/ethnicity and genetic ancestry with arterial elasticity: the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Soc Hypertens. 2011 Nov-Dec; 5(6):463-72.

Duprez DA, Jacobs DR, Lutsey PL, Bluemke DA, Brumback LC, Polak JF, Peralta CA, Greenland P, Kronmal RA. Association of small artery elasticity with incident cardiovascular disease in older adults: the multi-ethnic study of atherosclerosis. Am J Epidemiol. 2011 Sep 1; 174(5):528-36.

Peralta CA, Katz R, DeBoer I, Ix J, Sarnak M, Kramer H, Siscovick D, Shea S, Szklo M, Shlipak M. Racial and ethnic differences in kidney function decline among persons without chronic kidney disease. J Am Soc Nephrol. 2011 Jul; 22(7):1327-34.

Peralta CA, Shlipak MG, Judd S, Cushman M, McClellan W, Zakai NA, Safford MM, Zhang X, Muntner P, Warnock D. Detection of chronic kidney disease with creatinine, cystatin C, and urine albumin-to-creatinine ratio and association with progression to end-stage renal disease and mortality. JAMA. 2011 Apr 20; 305(15):1545-52.

Madero M, Wassel CL, Peralta CA, Najjar SS, Sutton-Tyrrell K, Fried LF, de Boer IH, Shlipak MG, Newman AB, Hausman D, Sarnak MJ, Kritchevsky SB, Ix JH. Markers of mineral metabolism are not associated with aortic pulse wave velocity in community-living elderly persons: the Health Aging and Body Composition study. Am J Hypertens. 2011 Jul; 24(7):755-61.

Böger CA, Chen MH, Tin A, Olden M, Köttgen A, de Boer IH, Fuchsberger C, O'Seaghdha CM, Pattaro C, Teumer A, Liu CT, Glazer NL, Li M, O'Connell JR, Tanaka T, Peralta CA, Kutalik Z, Luan J, Zhao JH, Hwang SJ, Akylbekova E, Kramer H, van der Harst P, Smith AV, Lohman K, de Andrade M, Hayward C, Kollerits B, Tönjes A, Aspelund T, Ingelsson E, Eiriksdottir G, Launer LJ, Harris TB, Shuldiner AR, Mitchell BD, Arking DE, Franceschini N, Boerwinkle E, Egan J, Hernandez D, Reilly M, Townsend RR, Lumley T, Siscovick DS, Psaty BM, Kestenbaum B, Haritunians T, Bergmann S, Vollenweider P, Waeber G, Mooser V, Waterworth D, Johnson AD, Florez JC, Meigs JB, Lu X, Turner ST, Atkinson EJ, Leak TS, Aasarød K, Skorpen F, Syvänen AC, Illig T, Baumert J, Koenig W, Krämer BK, Devuyst O, Mychaleckyj JC, Minelli C, Bakker SJ, Kedenko L, Paulweber B, Coassin S, Endlich K, Kroemer HK, Biffar R, Stracke S, Völzke H, Stumvoll M, Mägi R, Campbell H, Vitart V, Hastie ND, Gudnason V, Kardia SL, Liu Y, Polasek O, Curhan G, Kronenberg F, Prokopenko I, Rudan I, Arnlöv J, Hallan S, Navis G. CUBN is a gene locus for albuminuria. J Am Soc Nephrol. 2011 Mar; 22(3):555-70.

Shastri S, Katz R, Shlipak MG, Kestenbaum B, Peralta CA, Kramer H, Jacobs DR, de Boer IH, Cushman M, Siscovick D, Sarnak MJ. Cystatin C and albuminuria as risk factors for development of CKD stage 3: the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Kidney Dis. 2011 Jun; 57(6):832-40.

Dubin R, Cushman M, Folsom AR, Fried LF, Palmas W, Peralta CA, Wassel C, Shlipak MG. Kidney function and multiple hemostatic markers: cross sectional associations in the multi-ethnic study of atherosclerosis. BMC Nephrol. 2011; 12:3.

Peralta CA, Katz R, Sarnak MJ, Ix J, Fried LF, De Boer I, Palmas W, Siscovick D, Levey AS, Shlipak MG. Cystatin C identifies chronic kidney disease patients at higher risk for complications. J Am Soc Nephrol. 2011 Jan; 22(1):147-55.

Marcus GM, Alonso A, Peralta CA, Lettre G, Vittinghoff E, Lubitz SA, Fox ER, Levitzky YS, Mehra R, Kerr KF, Deo R, Sotoodehnia N, Akylbekova M, Ellinor PT, Paltoo DN, Soliman EZ, Benjamin EJ, Heckbert SR. European ancestry as a risk factor for atrial fibrillation in African Americans. Circulation. 2010 Nov 16; 122(20):2009-15.

Dubin R, Shlipak M, Li Y, Ix J, de Boer IH, Jenny N, Peralta CA. Racial differences in the association of pentraxin-3 with kidney dysfunction: the Multi-Ethnic Study of Atherosclerosis. Nephrol Dial Transplant. 2011 Jun; 26(6):1903-8.

Day EC, Li Y, Diez-Roux A, Kandula N, Moran A, Rosas S, Shlipak MG, Peralta CA. Associations of acculturation and kidney dysfunction among Hispanics and Chinese from the Multi-Ethnic Study of Atherosclerosis (MESA). Nephrol Dial Transplant. 2011 Jun; 26(6):1909-16.

Allison MA, Peralta CA, Wassel CL, Aboyans V, Arnett DK, Cushman M, Eng J, Ix J, Rich SS, Criqui MH. Genetic ancestry and lower extremity peripheral artery disease in the Multi-Ethnic Study of Atherosclerosis. Vasc Med. 2010 Oct; 15(5):351-9.

Campbell CY, Fang BF, Guo X, Peralta CA, Psaty BM, Rich SS, Young JH, Coresh J, Kramer HJ, Rotter JI, Post WS. Associations between genetic variants in the ACE, AGT, AGTR1 and AGTR2 genes and renal function in the Multi-ethnic Study of Atherosclerosis. Am J Nephrol. 2010; 32(2):156-62.

Peralta CA, Lin F, Shlipak MG, Siscovick D, Lewis C, Jacobs DR, Bibbins-Domingo K. Race differences in prevalence of chronic kidney disease among young adults using creatinine-based glomerular filtration rate-estimating equations. Nephrol Dial Transplant. 2010 Dec; 25(12):3934-9.

Peralta CA, Li Y, Wassel C, Choudhry S, Palmas W, Seldin MF, Risch N, Siscovick D, Arnett D, Psaty B, Shlipak MG. Differences in albuminuria between Hispanics and whites: an evaluation by genetic ancestry and country of origin: the multi-ethnic study of atherosclerosis. Circ Cardiovasc Genet. 2010 Jun; 3(3):240-7.

Ix JH, Katz R, Peralta CA, de Boer IH, Allison MA, Bluemke DA, Siscovick DS, Lima JA, Criqui MH. A high ankle brachial index is associated with greater left ventricular mass MESA (Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol. 2010 Jan 26; 55(4):342-9.

Peralta CA, Risch N, Lin F, Shlipak MG, Reiner A, Ziv E, Tang H, Siscovick D, Bibbins-Domingo K. The Association of African Ancestry and elevated creatinine in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Nephrol. 2010; 31(3):202-8.

Peralta CA, Adeney KL, Shlipak MG, Jacobs D, Duprez D, Bluemke D, Polak J, Psaty B, Kestenbaum BR. Structural and functional vascular alterations and incident hypertension in normotensive adults: the Multi-Ethnic Study of Atherosclerosis. Am J Epidemiol. 2010 Jan 1; 171(1):63-71.

Wassel CL, Pankow JS, Peralta CA, Choudhry S, Seldin MF, Arnett DK. Genetic ancestry is associated with subclinical cardiovascular disease in African-Americans and Hispanics from the multi-ethnic study of atherosclerosis. Circ Cardiovasc Genet. 2009 Dec; 2(6):629-36.

Madero M, Wassel CL, Peralta CA, Najjar SS, Sutton-Tyrrell K, Fried L, Canada R, Newman A, Shlipak MG, Sarnak MJ. Cystatin C associates with arterial stiffness in older adults. J Am Soc Nephrol. 2009 May; 20(5):1086-93.

Ix JH, De Boer IH, Peralta CA, Adeney KL, Duprez DA, Jenny NS, Siscovick DS, Kestenbaum BR. Serum phosphorus concentrations and arterial stiffness among individuals with normal kidney function to moderate kidney disease in MESA. Clin J Am Soc Nephrol. 2009 Mar; 4(3):609-15.

Peralta CA, Katz R, Madero M, Sarnak M, Kramer H, Criqui MH, Shlipak MG. The differential association of kidney dysfunction with small and large arterial elasticity: the multiethnic study of atherosclerosis. Am J Epidemiol. 2009 Mar 15; 169(6):740-8.

Peralta CA, Shlipak MG. Hypertension in children with chronic kidney disease: a call to action. Hypertension. 2008 Oct; 52(4):610-2.

Kestenbaum B, Rudser KD, de Boer IH, Peralta CA, Fried LF, Shlipak MG, Palmas W, Stehman-Breen C, Siscovick DS. Differences in kidney function and incident hypertension: the multi-ethnic study of atherosclerosis. Ann Intern Med. 2008 Apr 1; 148(7):501-8.

Peralta CA, Shlipak MG, Wassel-Fyr C, Bosworth H, Hoffman B, Martins S, Oddone E, Goldstein MK. Association of antihypertensive therapy and diastolic hypotension in chronic kidney disease. Hypertension. 2007 Sep; 50(3):474-80.

Peralta CA, Ziv E, Katz R, Reiner A, Burchard EG, Fried L, Kwok PY, Psaty B, Shlipak M. African ancestry, socioeconomic status, and kidney function in elderly African Americans: a genetic admixture analysis. J Am Soc Nephrol. 2006 Dec; 17(12):3491-6.

Peralta CA, Shlipak MG, Fan D, Ordoñez J, Lash JP, Chertow GM, Go AS. Risks for end-stage renal disease, cardiovascular events, and death in Hispanic versus non-Hispanic white adults with chronic kidney disease. J Am Soc Nephrol. 2006 Oct; 17(10):2892-9.

Peralta CA, Whooley MA, Ix JH, Shlipak MG. Kidney function and systolic blood pressure new insights from cystatin C: data from the Heart and Soul Study. Am J Hypertens. 2006 Sep; 19(9):939-46.

Peralta CA, Kurella M, Lo JC, Chertow GM. The metabolic syndrome and chronic kidney disease. Curr Opin Nephrol Hypertens. 2006 Jul; 15(4):361-5.

Peralta CA, Hicks LS, Chertow GM, Ayanian JZ, Vittinghoff E, Lin F, Shlipak MG. Control of hypertension in adults with chronic kidney disease in the United States. Hypertension. 2005 Jun; 45(6):1119-24.

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