Faculty Profiles

Anthony Sebastian, MD
M_MED-NEPH-CORE-GEN
Professor

505 Parnassus Avenue
San Francisco, CA 94117
415-476-1160
Anthony.Sebastian@ucsf.edu

EDUCATION


University of California, Los Angeles, B.S (Chemistry) -1960
University of California, San Francisco, M.D. - 1965
University of California, San Francisco, Internship & Residency, Medicine - 1966-1968
University of California, San Francisco, Nephrology Fellowship, - 1968-1972


INTERESTS

Education and Training

Location Degree or Training Specialty Date
University of California, San Francisco M.D. School of Medicine 1965
University of California, San Francisco Residency School of Medicine

Awards and Honors

2016   The Anthony & Patricia Sebastian Endowed Scholarship, UCSF Medical School Class of 1965, 2016
2005   ACADEMIC SENATE'S FIFTH ANNUAL DISTINGUISHED CLINICAL RESEARCH LECTURE, UCSF, 2005
2002   The Belding H. Scribner Award, American Society of Nephology, 2002
2002   School of Medicine Alumnus of the Year, UCSF, 2002
  Champion of Diversity Award, UCSF

Related Web Sites

Recent Articles (31)

Sebastian A, Frassetto LA. A neglected requirement for optimizing treatment of age-related osteoporosis: Replenishing the skeleton's base reservoir with net base-producing diets. Med Hypotheses. 2016 Jun; 91:103-8.

Morris RC, Schmidlin O, Sebastian A, Tanaka M, Kurtz TW. Vasodysfunction That Involves Renal Vasodysfunction, Not Abnormally Increased Renal Retention of Sodium, Accounts for the Initiation of Salt-Induced Hypertension. Circulation. 2016 Mar 1; 133(9):881-93.

Morris RC, Schmidlin O, Sebastian A, Tanaka M, Kurtz TW. Response to Hall. Circulation. 2016 Mar 1; 133(9):907.

Raphael KL, Murphy RA, Shlipak MG, Satterfield S, Huston HK, Sebastian A, Sellmeyer DE, Patel KV, Newman AB, Sarnak MJ, Ix JH, Fried LF. Bicarbonate Concentration, Acid-Base Status, and Mortality in the Health, Aging, and Body Composition Study. Clin J Am Soc Nephrol. 2016 Feb 5; 11(2):308-16.

Kalani L Raphael, Rachel A Murphy, Michael G Shlipak, Suzanne Satterfield, Hunter K Huston, Anthony Sebastian, Deborah E Sellmeyer, Kushang V Patel, Anne B Newman, Mark J Sarnak, Joachim H Ix, Linda F Fried . Bicarbonate concentration, acid-base status, and mortality in the health, aging, and body composition study. Clinical Journal of the American Society of Nephrology, CJN.06200615. 2016.

Frassetto LA, Sebastian A. Commentary to accompany the paper entitled 'nutritional disturbance in acid-base balance and osteoporosis: a hypothesis that disregards the essential homeostatic role of the kidney', by Jean-Philippe Bonjour. Br J Nutr. 2013 Dec 14; 110(11):1935-7.

Park-Sigal J, Don BR, Porzig A, Recker R, Griswold V, Sebastian A, Duh QY, Portale AA, Shoback D, Schambelan M. Severe hypercalcemic hyperparathyroidism developing in a patient with hyperaldosteronism and renal resistance to parathyroid hormone. J Bone Miner Res. 2013 Mar; 28(3):700-8.

Moseley KF, Weaver CM, Appel L, Sebastian A, Sellmeyer DE. Potassium citrate supplementation results in sustained improvement in calcium balance in older men and women. J Bone Miner Res. 2013 Mar; 28(3):497-504.

Frassetto LA, Hardcastle AC, Sebastian A, Aucott L, Fraser WD, Reid DM, Macdonald HM. No evidence that the skeletal non-response to potassium alkali supplements in healthy postmenopausal women depends on blood pressure or sodium chloride intake. Eur J Clin Nutr. 2012 Dec; 66(12):1315-22.

Frassetto LA, Sebastian A. How metabolic acidosis and oxidative stress alone and interacting may increase the risk of fracture in diabetic subjects. Med Hypotheses. 2012 Aug; 79(2):189-92.

Schmidlin O, Forman A, Leone A, Sebastian A, Morris RC. Salt sensitivity in blacks: evidence that the initial pressor effect of NaCl involves inhibition of vasodilatation by asymmetrical dimethylarginine. Hypertension. 2011 Sep; 58(3):380-5.

Ströhle A, Hahn A, Sebastian A. Latitude, local ecology, and hunter-gatherer dietary acid load: implications from evolutionary ecology. Am J Clin Nutr. 2010 Oct; 92(4):940-5.

Schmidlin O, Tanaka M, Sebastian A, Morris RC. Selective chloride loading is pressor in the stroke-prone spontaneously hypertensive rat despite hydrochlorothiazide-induced natriuresis. J Hypertens. 2010 Jan; 28(1):87-94.

Ströhle A, Hahn A, Sebastian A. Estimation of the diet-dependent net acid load in 229 worldwide historically studied hunter-gatherer societies. Am J Clin Nutr. 2010 Feb; 91(2):406-12.

Frassetto LA, Schloetter M, Mietus-Synder M, Morris RC, Sebastian A. Metabolic and physiologic improvements from consuming a paleolithic, hunter-gatherer type diet. Eur J Clin Nutr. 2009 Aug; 63(8):947-55.

Frassetto LA, Morris RC, Sellmeyer DE, Sebastian A. Adverse effects of sodium chloride on bone in the aging human population resulting from habitual consumption of typical American diets. J Nutr. 2008 Feb; 138(2):419S-422S.

Schmidlin O, Forman A, Sebastian A, Morris RC. Sodium-selective salt sensitivity: its occurrence in blacks. Hypertension. 2007 Dec; 50(6):1085-92.

Frassetto LA, Lanham-New SA, Macdonald HM, Remer T, Sebastian A, Tucker KL, Tylavsky FA. Standardizing terminology for estimating the diet-dependent net acid load to the metabolic system. J Nutr. 2007 Jun; 137(6):1491-2.

Frassetto LA, Morris RC, Sebastian A. Dietary sodium chloride intake independently predicts the degree of hyperchloremic metabolic acidosis in healthy humans consuming a net acid-producing diet. Am J Physiol Renal Physiol. 2007 Aug; 293(2):F521-5.

Sebastian A, Frassetto LA, Sellmeyer DE, Morris RC. The evolution-informed optimal dietary potassium intake of human beings greatly exceeds current and recommended intakes. Semin Nephrol. 2006 Nov; 26(6):447-53.

Morris RC, Schmidlin O, Frassetto LA, Sebastian A. Relationship and interaction between sodium and potassium. J Am Coll Nutr. 2006 Jun; 25(3 Suppl):262S-270S.

Sebastian A. Protein consumption as an important predictor of lower-limb bone mass in elderly women. Am J Clin Nutr. 2005 Dec; 82(6):1355-6; author reply 1356.

Sebastian A. Dietary protein content and the diet's net acid load: opposing effects on bone health. Am J Clin Nutr. 2005 Nov; 82(5):921-2.

Sebastian A. Isoflavones, protein, and bone. Am J Clin Nutr. 2005 Apr; 81(4):733-5.

Cordain L, Eaton SB, Sebastian A, Mann N, Lindeberg S, Watkins BA, O'Keefe JH, Brand-Miller J. Origins and evolution of the Western diet: health implications for the 21st century. Am J Clin Nutr. 2005 Feb; 81(2):341-54.

Frassetto L, Morris RC, Sebastian A. Long-term persistence of the urine calcium-lowering effect of potassium bicarbonate in postmenopausal women. J Clin Endocrinol Metab. 2005 Feb; 90(2):831-4.

Sebastian A. Low versus high meat diets: effects on calcium metabolism. J Nutr. 2003 Oct; 133(10):3237-8; author reply 3240.

Sebastian A, Frassetto LA, Sellmeyer DE, Merriam RL, Morris RC. Estimation of the net acid load of the diet of ancestral preagricultural Homo sapiens and their hominid ancestors. Am J Clin Nutr. 2002 Dec; 76(6):1308-16.

Morris RC, Sebastian A. Alkali therapy in renal tubular acidosis: who needs it? J Am Soc Nephrol. 2002 Aug; 13(8):2186-8.

Sellmeyer DE, Schloetter M, Sebastian A. Potassium citrate prevents increased urine calcium excretion and bone resorption induced by a high sodium chloride diet. J Clin Endocrinol Metab. 2002 May; 87(5):2008-12.

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