Fellows' Research

Examples from Recently Graduated Research Fellows

 

 Jonathan Amatruda, MD, MAS (started research training 2019)

Research Mentors: Michelle Estrella, MD, MHS; Michael Shlipak, MD, MPH
Project: The overarching goal of my research is to develop new ways to measure kidney health in order to improve the detection, treatment, and prevention of kidney disease. My current research project uses biomarkers of kidney tubule function and injury to study potentially nephrotoxic medications, specifically non-steroidal anti-inflammatory drugs.  
Training: Completed master's program in clinical research from UCSF Department of Epidemiology and Biostatistics. 

Grant Funding, Selected Publications and Presentations

Grant Funding:

  • UCSF Division of Nephrology T32
  • F32 

Selected Publications:

  • Amatruda JG, Scherzer R, Rao VS, Ivey-Miranda JB, Shlipak MG, Estrella MM, Testani JM. Renin-Angiotensin-Aldosterone System Activation and Diuretic Response in Ambulatory Patients With Heart Failure. Kidney Med. 2022 Apr 8;4(6):100465.
  • Amatruda JG, Katz R, Sarnak MJ, Gutierrez OM, Greenberg JH, Cushman M, Waikar S, Parikh CR, Schelling JR, Jogalekar MP, Bonventre JV, Vasan RS, Kimmel PL, Shlipak MG, Ix JH. Biomarkers of Kidney Tubule Disease and Risk of End-Stage Kidney Disease in Persons With Diabetes and CKD. Kidney Int Rep. 2022 Apr 5;7(7):1514-1523.
  • Ivey-Miranda JB, Stewart B, Cox ZL, McCallum W, Maulion C, Gleason O, Meegan G, Amatruda JG, Moreno-Villagomez J, Mahoney D, Turner JM, Wilson FP, Estrella MM, Shlipak MG, Rao VS, Testani JM. FGF-23 (Fibroblast Growth Factor-23) and Cardiorenal Interactions. Circ Heart Fail. 2021 Nov;14(11):e008385.
  • Amatruda JG, Katz R, Peralta CA, Estrella MM, Sarathy H, Fried LF, Newman AB, Parikh CR, Ix JH, Sarnak MJ, Shlipak MG, Health ABC Study. Association of non-steroidal anti-inflammatory drugs with kidney health in ambulatory older adults. J Am Geriatr Soc. 2021; 69: 726–734.
  • Amatruda JG, Estrella ME, Garg AX, Thiessen-Philbrook H, McArthur E, Coca SG, Parikh CR, Shlipak MG. Urine alpha-1-microglobulin levels and acute kidney injury, mortality and cardiovascular events following cardiac surgery. Am J Nephrol. 2021;52:673–683. 

Selected Presentations:

  • Am Soc Neph Kidney Week
  • National Clinician Consultation Center

Matthew Breeggemann, MD (started research training 2021)

Research Mentor: Onur Cil, MD, PhD
Project: The overarching goal of my research is to advance novel treatment approaches for hyperoxaluria and calcium oxalate nephrolithiasis. We are studying novel drug candidates for their effects on gastrointestinal oxalate transport and potential efficacy in mouse models of hyperoxaluria.

Grant Funding, Selected Publications and Presentations

Grant Funding:

  • UCSF Division of Nephrology T32
  • UCSF Molecular Medicine in Nephrology

Selected Publications:

  • Breeggemann MC, Gluck SL. Transient Hyperkalemia Following Treatment of Chronic Hypokalemia: A Case Report and Review of Distal Tubule Physiology. Case Rep Nephrol Dial. 2022 Jan 31;12(1):1-4.
  • Kikuchi K, Saigusa D, Kanemitsu Y, Matsumoto Y, Thanai P, Suzuki N, Mise K, Yamaquchi H, Nakamura T, Asaji K, Mukawa C, Tsukamoto H, Sato T, Oikawa Y, Iwasaki T, Oe Y, Tsukimi T, Fukuda NN, Ho HJ, Nanto-Hara F, Ogura J, Saito R, Nagao S, Ohsaki Y, Shimada S, Suzuki T, Toyohara T, Mishima E, Shima H, Akiyama Y, Ichijo M, Matsuhashi T, Matsuo A, Ogata Y, Yang CC, Suzuki C, Breeggemann MC, Heymann J, Shimizu M, Ogawa S, Takahashi N, Suzuki T, Owada Y, Kure S, Mano N, Soga T, Wada T, Kopp JB, Fukuda S, Hozawa A, Yamamoto M, Ito S, Wada J, Tomioka Y, Abe T. Gut microbiome-derived phenyl sulfate is a cause and predictive marker of albuminuria in diabetic kidney disease. Nat Commun. 2019; 10: 1835.  
  • Wang Y, Chang J, Yao B, Niu A, Kelly E, Breeggemann MC, Abboud Werner SL, Harris RC, Zhang MZ. Proximal tubule-derived CSF-1 mediates polarization of renal macrophages and dendritic cells and recovery in acute kidney injury. Kidney Int. 2015; 88: 1274-1282.  

Debbie Chen, MD, MAS (started research training 2020)

Research Mentors: Michelle Estrella, MD, MHS; Michael Shlipak, MD, MPH
Project: The overarching goal of my research is to use cystatin C to improve the efficacy and safety of medication dosing in patients with CKD. 
Training: Completed master's program in clinical research from UCSF Department of Epidemiology and Biostatistics.

Grant Funding, Selected Publications and Presentations

Grant Funding:

  • UCSF Division of Nephrology T32
  • F32

Selected Publications:

  • Chen DC, Shlipak MG, Scherzer R, Bansal N, Potok OA, Rifkin DE, Ix JH, Muiru AN, Hsu CY, Estrella MM. Association of Intra-individual Differences in Estimated GFR by Creatinine Versus Cystatin C With Incident Heart Failure. Am J Kidney Dis. 2022 Jul 9:S0272-6386(22)00770-3. Epub ahead of print.
  • Chen DC, Shlipak MG, Scherzer R, Bauer SR, Potok OA, Rifkin DE, Ix JH, Muiru AN, Hsu CY, Estrella MM. Association of Intraindividual Difference in Estimated Glomerular Filtration Rate by Creatinine vs Cystatin C and End-stage Kidney Disease and Mortality. JAMA Netw Open. 2022 Feb 1;5(2):e2148940.
  • Weir MR, Chen DC, Ku E. Should renin-angiotensin system blockade be avoided in patients with declining kidney function? Am J Kidney Dis.  2020; S0272-6386(20)30671-5.
  • Chen DC, McCallum W, Sarnak MJ, Ku E. Intensive BP control and eGFR declines: are these events due to hemodynamic effects and are changes reversible? Curr Cardiol Rep. 2020; 22: 117.

 Chi Chu, MD, MAS (started research training 2018)

Research mentor: Delphine Tuot, MDCM, MAS
Project: Leveraging large clinical datasets to improve delivery of CKD care, with a particular focus on the application of risk prediction to guide clinical decision making.
Training: Completed master's program in clinical research from UCSF Department of Epidemiology and Biostatistics

Grant Funding, Selected Publications and Presentations

Grant Funding:

  • UCSF Division of Nephrology T32
  • F32

Selected Publications:

  • Chu CD, Powe NR, McCulloch CE, Banerjee T, Crews DC, Saran R, Bragg-Gresham J, Morgenstern H, Pavkov ME, Saydah SH, Tuot DS. Angiotensin-converting enzyme inhibitor or angiotensin receptor blocker use among hypertensive US adults with albuminuria. Hypertension. 2021; 77: 94-102.
  • Chu CD, Chen MH, McCulloch CE, Powe NR, Estrella MM, Shlipak MG, Tuot DS. Patient awareness of CKD: a systematic review and meta-analysis of patient-oriented questions and study setting. Kidney Med. 2021; 3: 576-585.
  • Chu CD, Tuot DS, Harrison JD, Duong J, Luxenberg A, Khanna RR. Completeness and quality of text paging for subspecialty consult requests. Postgrad Med J. 2021; 97 : 511-514.
  • Chu CD, McCulloch CE, Banerjee T, Pavkov ME, Burrows NR, Gillespie BW, Saran R, Shlipak MG, Powe NR, Tuot DS. CKD awareness among U.S. adults by future risk of kidney failure. Am J Kidney Dis. 2020; 76: 174-183.
  • Chu CD, Ku E, Fallahzadeh MK, McCulloch CE, Tuot DS. The Kidney Failure Risk Equation for prediction of allograft loss in kidney transplant recipients. Kidney Med. 2020 Oct 28; 2: 753-761.
  • Tummalapalli SL, Chu CD, Tuot DS. Avoiding overuse of venipuncture and laboratory testing in hospitalized patients on hemodialysis. J Patient Saf. 2020 Jun 19: 10.1097/PTS.0000000000000738.
  • Lee J, Chu CD, Guzman D, Fontil V, Velasquez A, Powe NR, Tuot DS. Albuminuria testing by race and ethnicity among patients with hypertension with and without diabetes. Am J Nephrol. 2019; 50: 48-54.

Selected Presentations:

  • Am Soc Neph Kidney Week
  • American Medical Informatics Association Annual Symposium

John Demko, MD (started research training 2020)

Research Mentor: David Pearce, MD
Project: The overarching goal of my research is is focused on the molecular mechanisms of sodium, potassium, and glucose homeostasis in the kidney. Building on prior work with SGK-1 and aldosterone signaling pathways, we are now focused on mTOR complex 2 and its role in ENaC and potassium transport in the distal nephron. Our group is also working to define the mechanism of potassium-sensing within the kidney and the role of WNK kinases. We primarily use transgenic mice and cell culture models for our work. Globally, I am interested in mechanisms of hypertension, metabolic syndrome, electrolyte homeostasis, and identifying novel therapeutic targets for these disorders. 

Grant Funding, Selected Publications and Presentations

Grant Funding:

  • UCSF Division of Nephrology T32
  • UCSF Molecular Medicine in Nephrology

Selected Publications:

  • Ray EC, Miller RG, Demko JE, Costacou T, Kinlough CL, Demko CL, Unruh ML, Orchard TJ, Kleyman TR.  Urinary plasmin(ogen) as a prognostic factor for hypertension. Kidney Int Rep. 2018; 3: 1434-1442.
  • Unruh ML, Pankratz VS, Demko JE, Ray EC, Hughey RP, Kleyman TR. Trial of amiloride in type 2 diabetes with proteinuria. Kidney Int Rep. 2017; 2: 893-904.

Selected Presentations:

  • UCSF Floyd Rector Symposium

Alex Dinh, MD, MAS (started research training 2020) 

Research Mentor: Elaine Ku, MD, MAS
Project: An individualized approach to identifying risk for serious infections and infection-related kidney outcomes in kidney transplant recipients.
Training: Completed master's program in clinical research from UCSF Department of Epidemiology and Biostatistics

Grant Funding, Selected Publications and Presentations

Grant Funding:

  • UCSF Division of Nephrology T32
  • F32

Selected Publications:

  • Whelan AM, Dinh A, Ku E. Kidney Transplantation in the Setting of Prolonged Dialysis Vintage: It's About Time. Am J Kidney Dis. 2022 Sep;80(3):307-308. ​​​​​​​
  • Dinh AR, Wong SW, Martin TG, Wolf JL, Webber AB. Outcomes of kidney transplant recipients with ESKD due to plasma cell dyscrasia: A case series. Clin Transplant. 2022 Mar;36(3):e14541.
  • Dinh A, Copeland T, Freedman BI, McCulloch CE, Ku E. Intensive Blood Pressure Control, APOL1 Genotype, and Kidney Outcomes in Individuals With Type 2 Diabetes: A Post Hoc Analysis of the Action to Control Cardiovascular Risk in Diabetes-Blood Pressure (ACCORD-BP) Trial. Kidney Med. 2021 Jul 10;3(5):874-876.
  • Dinh A, McCulloch CE, Ku E. Predicting long-term kidney allograft outcomes: pitfalls and progress. Kidney Int. 2021; 99: 24-26.
  • Dinh A, Ku E. Pre-transplant dialysis exposure and outcomes after kidney transplantation–where quantity and quality intersect? Am J Transplant. 2020; 20: 2301-2302.
  • Cortazar FB, Kibbelaar ZA, Glezerman IG, Abudayyeh A, Mamlouk O, Motwani SS, Murakami N, Herrmann SM, Manohar S, Shirali AC, Kitchlu A, Shirazian S, Assal A, Vijayan A, Renaghan AD, Ortiz-Melo DI, Rangarajan S, Malik AB, Hogan JJ, Dinh AR, Shin DS, Marrone KA, Mithani Z, Johnson DB, Hosseini A, Uprety D, Sharma S, Gupta S, Reynolds KL, Sise ME, Leaf DE. Clinical features and outcomes of immune checkpoint inhibitor-associated AKI: a multicenter study. J Am Soc Nephrol. 2020; 31: 435-446.
  • Dinh A, Palmer MB, Svoboda J, Hogan JJ.  Lenalidomide-induced tubulointerstitial nephritis in Hodgkin lymphoma. Leuk Lymphoma. 2019; 60: 3084-3086.

Selected Presentations:

  • Am Soc Neph Kidney Week

Diana Kwong, MD, MAS (started research training 2017)

Research Mentor: Kathleen Liu, MD, PhD, MAS
Project descriptions: Biomarkers and outcomes of acute kidney injury
Training: Completed master's program in clinical research from UCSF Department of Epidemiology and Biostatistics

Grant Funding, Selected Publications and Presentations

Grant Funding:

  • UCSF Division of Nephrology T32
  • Am Soc Neph fellowship grant
  • F32

Selected Publications:

  • Kwong YD, Liu KD, Lo LJ. Outpatient Dietary Management of Electrolyte Disorders During COVID-19: Food as Medicine. JAMA Intern Med. 2021 May 1;181(5):581-582.
  • Kwong YD, Liu KD, Hsu RK. Kidney Dysfunction After Acute Heart Failure: Is Acute Kidney Disease the New Acute Kidney Injury? Kidney Int Rep. 2021 Dec 31;7(3):378-380.
  • Kwong YD, Liu KD, Hsu RK, Johansen KL, McCulloch CE, Seth D, Fallahzadeh MK, Grimes BA, Ku E. Recovery of kidney function among patients with glomerular disease starting maintenance dialysis. Am J Kidney Dis. 2021; 77: 303-305.
  • Kwong YD, Mehta KM, Miaskowski C, Zhuo H, Yee K, Jauregui A, Ke S, Deiss T, Abbott J, Kangelaris KN, Sinha P, Hendrickson C, Gomez A, Leligdowicz A, Matthay MA, Calfee CS, Liu KD. Using best subset regression to identify clinical characteristics and biomarkers associated with sepsis-associated acute kidney injury. Am J Physiol Renal Physiol. 2020 Dec 1;319(6):F979-F987.
  • Kwong YD, Mehta KM, Miaskowski C, Zhuo H, Yee K, Jauregui A, Ke S, Deiss T, Abbott J, Kangelaris KN, Sinha P, Hendrickson C, Gomez A, Leligdowicz A, Matthay MA, Calfee CS, Liu KD.  Using best subset regression to identify clinical characteristics and biomarkers associated with sepsis-associated acute kidney injury. Am J Physiol Renal Physiol. 2020; 319: F979-F987.
  • Kwong YD, Liu KD. Prediction models for AKI: will they result in improved outcomes for AKI? Clin J Am Soc Nephrol. 2019; 14: 488-49.
  • Kwong YD, Chen S, Bouajram R, Li F, Matthay MA, Mehta KM, Glidden DV, Liu KD. The value of kinetic glomerular filtration rate estimation on medication dosing in acute kidney injury. PLoS One. 2019; 14: e0225601.​​​​​​
  • Kwong YD, Liu KD. AKI adjudication: do we need it. Nephron. 2017; 137: 294-296.
  • Kwong YD, Liu KD. Selection of intravenous fluids. Am J Kidney Dis. 2018; 72: 900-902.
  • Kwong YD, Stevens LA, Selvin E, Zhang YL, Greene T, Van Lente F, Levey AS, Coresh J. Imprecision of urinary iothalamate clearance as a gold-standard measure of GFR decreases the diagnostic accuracy of kidney function estimating equations. Am J Kidney Dis. 2010; 56: 39-49.

Selected Presentations:

  • Am Soc Neph Kidney Week

  • NKF Northern California

Dana Larsen, MD (started research training 2021)

Research Mentors: Christy Boscardin, PhD; Leticia Rolon, MD 
Project: The overarching goal of my research will focus on the evaluation of the use of social media on graduate medical education, specifically looking at filling current gaps in knowledge acquisition from training programs. 
Training: Enrolled in Master's in Medical Education from a combined program at UCSF & UC Berkeley

Grant Funding, Selected Publications and Presentations

Selected Publications:

  • Larsen D, Chu JT, Yu L, Chang Y, Donelan K, Palamara K. Correlating burnout and well-being in a multisite study of internal medicine residents and faculty. J Gen Intern Med. 2021; 36: 1422-1426.
  • Larsen DM, Tangren JS. Trends in Chronic Hypertension in Pregnancy Highlight Racial Disparities in Maternal Health. Hypertension. 2019 Nov;74(5):1087-1088.

Selected Presentations:

  • Society of General Internal Medicine (SGIM) Meeting
  • Am Soc Neph Kidney Week

Benjamin Lee, MD, MAS (started research training 2016)

Research Mentor: Chi-yuan Hsu, MD, MSc
Project: Our research centered on studying the risk factors for and the implications of recovery vs. non-recovery from dialysis-requiring acute kidney injury (AKI-D).
Training: Completed master's program in clinical research from UCSF Department of Epidemiology and Biostatistics

Grant Funding, Selected Publications and Presentations

Grant Funding:

  • UCSF Division of Nephrology T32
  • F32

Selected Publications:

  • Ku E, Lee BJ, Wei J, Weir MR. Hypertension in CKD: Core Curriculum 2019. Am J Kidney Dis. 2019; 1:120-131
  • Chen Z, Lee BJ, McCulloch CE, Burrows NR, Heung M, Hsu RK, Pavkov ME, Powe NR, Saran R, Shahinian V, Hsu CY. The relation between dialysis-requiring acute kidney injury and recovery from end-stage renal disease: a national study.  BMC Nephrol 2019; 20: 342.
  • Lee BJ, Hsu CY, Parikh R, McCulloch CE, Tan TC, Liu KD, Hsu RK, Pravoverov L, Zheng S, Go AS. Predicting renal recovery after dialysis-requiring acute kidney injury. Kidney Int Rep. 2019; 4: 571-581.
  • Lee BJ, Go AS, Parikh R, Leong TK, Tan TC, Walia S, Hsu RK, Liu KD, Hsu CY. Pre-admission proteinuria impacts risk of non-recovery after dialysis-requiring acute kidney injury. Kidney Int. 2018; 93: 968-976.
  • Lee BJ, Hsu CY, Parikh RV, Leong TK, Tan TC, Walia S, Liu KD, Hsu RK, Go AS.  Non-recovery from dialysis-requiring acute kidney injury and short-term mortality and cardiovascular risk: a cohort study. BMC Nephrol. 2018; 19: 134.   
  • Lee BJ, Johansen KL, McCullouch CE, Hsu CY. Potential impact of Medicare payment policy on misclassification of dialysis-requiring acute kidney injury as ESRD: a national temporal trend analysis. Am J Kidney Dis. 2018; 72 :311-313.
  • Lee BJ, McCulloch CE, Grimes BA, Chandran S, Allen IR, Delgado C, Hsu CY. Refining the policy for timing of kidney transplant waitlist qualification. Transplantation Direct 2017; 3:  e195.  
  • Lee BJ, Hsu CY. Acute kidney injury is important in the hospital and afterward.  J Hosp Med. 2017; 12: 126-127. 

Selected Presentations:

  • Am Soc Neph Kidney Week

Gabriel Loeb, MD, PhD (started research training 2019)

Research Mentor: Jeremy Reiter, MD, PhD
Project: Leveraging genetics to identify mechanisms of chronic kidney disease.
Training: Completed a PhD in immunology at Sloan Kettering/Cornell Medical College

Grant Funding, Selected Publications and Presentations

Grant Funding:

  • UCSF Division of Nephrology T32
  • UCSF Molecular Medicine in Nephrology
  • UCSF Physician Scientist Scholar Program (PSSP)

Selected Publications:

  • Hsin JP,* Lu Y,* Loeb GB,* Leslie CS, Rudensky AY. The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types. Nat Immunol. 2018: 19: 1137-1145 (*equal contributors).
  • Loeb GB,* Khan AA,* Canner D, Hiatt JB, Shendure J, Darnell RB, Leslie CS, Rudensky AY. Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting. Mol Cell. 2012; 48: 760-70 (*equal contributors).

Ashley Martinez, MD (started research training 2021)

Research Mentors: Delphine Tuot, MDCM, MAS; Alicia Fernandez, MD; Neil Powe, MD, MBA, MPH
Project: The overarching goal of my research is the characterization of Latinx patients with limited English proficiency (LEP) in the United States who have or are at risk for chronic kidney disease (CKD) and identification of tailored interventions which may mitigate adverse impacts of language barriers and improve health outcomes.
Training: Enrolled in master’s program in clinical research from UCSF Department of Epidemiology and Biostatistics.

Grant Funding, Selected Publications and Presentations

Grant Funding:

  • UCSF Division of Nephrology T32

Anthony Muiru, MD, MPH (started research training 2017)

Research mentors: Chi-yuan Hsu, MD MSc; Michelle Estrella, MD MHS
Project description: Epidemiology of CKD in rural Kenya and Uganda. Novel Biomarkers of Kidney injury in the setting of HIV.

Grant Funding, Selected Publications and Presentations

Grant Funding:

  • UCSF Division of Nephrology T32
  • UCSF Dean’s Diversity Award

Selected Publications:

  • Muiru AN, Madden E, Chilingirian A, Rubinsky AD, Scherzer R, Moore R, Villalobos CPC, Monroy Trujillo JM, Parikh CR, Hsu CY, Shlipak MG, Estrella MM. The incidence of and risk factors for hospitalized acute kidney injury among people living with HIV on antiretroviral treatment. HIV Med. 2022 Jul;23(6):611-619.
  • Muiru AN, Yang J, Derebail VK, Liu KD, Feldman HI, Srivastava A, Bhat Z, Saraf SL, Chen TK, He J, Estrella MM, Go AS, Hsu CY. Black and White Adults With CKD Hospitalized With Acute Kidney Injury. Am J Kidney Dis. 2022 Apr 8:S0272-6386(22)00583-2. doi: 10.1053/j.ajkd.2022.02.021. Online ahead of print.
  • Muiru AN, Scherzer R, Ascher SB, Jotwani V, Grunfeld C, Shigenaga J, Spaulding KA, Ng DK, Gustafson D, Spence AB, Sharma A, Cohen MH, Parikh CR, Ix JH, Estrella MM, Shlipak MG. Associations of CKD risk factors and longitudinal changes in urine biomarkers of kidney tubules among women living with HIV. BMC Nephrol. 2021 Aug 30;22(1):296.
  • Muiru AN, Charlebois ED, Balzer LB, Kwarisiima D, Elly A, Black D, Okiror S, Kabami J, Atukunda M, Snyman K, Petersen M, Kamya M, Havlir D, Estrella MM, Hsu CY. The epidemiology of chronic kidney disease (CKD) in rural East Africa: A population-based study. PLoS One. 2020; 15: e0229649.
  • Muiru AN, Shlipak MG, Scherzer R, Zhang WR, Ascher SB, Jotwani V, Grunfeld C, Parikh CR, Ng D, Palella FJ, Jr., Ho K, Kassaye S, Sharma A, Cohen M, Wang R, Qi Q, Estrella MM. Kidney disease risk factors associate with urine biomarkers concentrations in HIV-positive persons; a cross-sectional study. BMC Nephrol. 2019; 20: 4
  • Zhang WR, Scherzer R, Estrella MM, Ascher SB, Muiru AN, Jotwani V, Grunfeld C, Parikh CR, Gustafson D, Kassaye S, Sharma A, Cohen M, Tien PC, Ng DK, Palella FJ, Jr., Witt MD, Ho K, Shlipak MG. Tenofovir disoproxil fumarate initiation and changes in urinary biomarker concentrations among HIV-infected men and women. AIDS. 2019; 33 :723-733.
  • Ascher SB, Scherzer R, Estrella MM, Zhang WR, Muiru AN, Jotwani V, Grunfeld C, Parikh CR, Gustafson D, Young M, Sharma A, Cohen MH, Ng DK, Palella FJ, Witt MD, Ho K, Shlipak MG. Association of urinary biomarkers of kidney injury with estimated GFR decline in HIV-infected individuals following tenofovir disoproxil fumarate initiation. Clin J Am Soc Nephrol. 2018; 13: 1321-1329.

Selected Presentations:

  • Am Soc Neph Kidney Week
  • Conference on Retroviruses and Opportunistic Infections (CROI)

Sri Lekha Tummalapalli, MD, MBA, MAS (started research training 2018)

Research Mentors: Michelle Estrella, MD MHS; Michael Shlipak, MD MPH; Salomeh Keyhani, MD MPH
Project: Population health and value-based strategies to deliver high quality care for patients with kidney disease. Patients with chronic kidney disease have had substantial gaps in chronic disease management and quality of care over the past decade. Medicaid expansion is not associated with improvements in kidney disease awareness or primary care delivery using quasi-experimental research designs.
Training: Completed master's program in clinical research from UCSF Department of Epidemiology and Biostatistics

Grant Funding, Selected Publications and Presentations

Grant Funding:

  • UCSF Division of Nephrology T32
  • Am Soc Neph fellowship grant
  • F32

Selected Publications:

  • Lamprea-Montealegre JA, Madden E, Tummalapalli SL, Peralta C, Neilands TB, Garcia PK, Muiru A, Karliner L, Shlipak MG, Estrella MM. Association of Race and Ethnicity With Prescription of SGLT2 Inhibitors and GLP1 Receptor Agonists Among Patients With Type 2 Diabetes in the Veterans Health Administration System. JAMA. 2022 Sep 6;328(9):861-871.
  • Shlipak MG, Tummalapalli SL, Boulware LE, Grams ME, Ix JH, Jha V, Kengne AP, Madero M, Mihaylova B, Tangri N, Cheung M, Jadoul M, Winkelmayer WC, Zoungas S; Conference Participants. The case for early identification and intervention of chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int. 2021 Jan;99(1):34-47.
  • Tummalapalli SL, Zelnick LR, Andersen AH, Christenson RH, deFilippi CR, Deo R, Go AS, He J, Ky B, Lash JP, Seliger SL, Soliman EZ, Shlipak MG, Bansal N. Association of Cardiac Biomarkers With the Kansas City Cardiomyopathy Questionnaire in Patients With Chronic Kidney Disease Without Heart Failure. J Am Heart Assoc. 2020 Jul 7;9(13):e014385. doi: 10.1161/JAHA.119.014385. Epub 2020 Jun 24. PMID: 32578483; PMCID: PMC7670503.
  • Tummalapalli SL, A Chang B, R Goodlev E. Physician practices in against medical advice discharges. J Healthc Qual. 2020; 42: 269-277.
  • Tummalapalli SL, Keyhani S. Trends in preventative health services for veterans with military coverage compared to non-military coverage. J Gen Intern Med. 2020; 35: 1330-1333
  • Tummalapalli SL, Vittinghoff E, Crews DC, Cushman M, Gutiérrez OM, Judd SE, Kramer HJ, Peralta CA, Tuot DS, Shlipak MG, Estrella MM. Chronic kidney disease awareness and longitudinal health outcomes: results from the REasons for Geographic And Racial Differences in Stroke study. Am J Nephrol. 2020; 51: 463-472.
  • Mendu ML, Tummalapalli SL, Lentine KL, Erickson KF, Lew SQ, Liu F, Gould E, Somers M, Garimella PS, O'Neil T, White DL, Meyer R, Bieber SD, Weiner DE. Measuring quality in kidney care: an evaluation of existing quality metrics and approach to facilitating improvements in care delivery. J Am Soc Nephrol. 2020; 31: 602-614.
  • Tummalapalli SL, Keyhani S. Changes in preventative health care after medicaid expansion. Med Care. 2020; 58: 549-556.
  • Tummalapalli SL, Estrella MM. Predicting risk of kidney disease: is risk-based kidney care on the horizon? JAMA. 2019; 322: 2079-81.
  • Tummalapalli SL, Peralta CA. Preparing the nephrology workforce for the transformation to value-based kidney care: needs assessment for advancing American kidney health. Clin J Am Soc Nephrol. 2019; 14: 1802-1804.
  • Tummalapalli SL, Peralta CA. An electronic CKD phenotype: a step forward in improving kidney care. Clin J Am Soc Nephrol. 2019; 14: 1277-1279.
  • Tummalapalli SL, Powe NR, Keyhani S. Trends in quality of care for patients with CKD in the United States. Clin J Am Soc Nephrol. 2019; 14: 1142-1150.
  • Tummalapalli SL, Shlipak MG. Hyperfiltration: much ado about nothing? Clin J Am Soc Nephrol. 2019; 14: 789-791.
  • Tummalapalli SL, Leonard S, Estrella MM, Keyhani S. The effect of medicaid expansion on self-reported kidney disease. Clin J Am Soc Nephrol. 2019; 14: 1238-1240.
  • Tummalapalli SL. Three hours, three days a week. Am J Kidney Dis. 2019; 73: A1.

Selected Presentations:

  • Am Soc Neph Kidney Week
  • AcademyHealth Annual Research Meeting