Basic Science Research Track

Basic Science Research Scientist (3-4 years)

UCSF has an international reputation for excellence in research and in training of graduate students and postgraduate scholars. Fellows in the Nephrology Training Program enjoy an unparalleled opportunity to participate in this extraordinary environment.

The goal of the basic science research program is to provide comprehensive training for a successful career as a physician-scientist in academic medicine through basic science courses and laboratory research.

Numerous research opportunities are available within the Division of Nephrology and in other Divisions and Departments at UCSF. Major areas of research include tubule molecular physiology and cell biology; renal immunology; human genetics in nephrology; renal injury, metabolism, and fibrosis; and renal development and stem cell biology. Additional research opportunities are available to work in basic science laboratories at UCSF to become skilled in techniques of molecular biology, biochemistry, cell physiology, and immunology. The "Molecular Medicine in Nephrology” program provides selected bench-research physician-scientist fellows $40,000 funding to support their research. Visit Basic and Translational research for more information on basic science research in nephrology at UCSF.

Basic Research Training, Facilities, and Resources

Formal didactic training and education is available through the Biomedical Sciences Program at UCSF. Coursework includes ethics and responsible conduct of research, cell biology, and basic science journal club. Additional coursework may be designated by the fellow's mentor and/or research committee.

Over 20000 sq. ft. of space is available for research training.

Including laboratories and other research space in the Division of Nephrology at Parnassus (5000 sq. ft.), SFVAMC (3500 sq. ft.), SFGH (1500 sq. ft.), and Mission Bay (1500 sq. ft.), and laboratories of the other participating training faculty. Equipment available in these laboratories includes: absorption and fluorescence spectrometers, fluorescent plate readers, phosphorimagers, phase contrast, confocal, and fluorescence microscopes, total internal reflectance microscope, equipment for measurement of fluorescence lifetimes and anisotropy, lasers, micropuncture and microinjection equipment, extensive tissue culture facilities, computers, electron microscopes, high performance liquid chromatography, scintillation counters, molecular biology equipment, cell sorters.

UCSF has abundant basic science core resources available to trainees.

Core laboratories and facilities available at UCSF include MicroArray cores, the Genomics and Bioinformatics core, the Comparative Genomic Hybridization core, the Genomics Core Facility, the Biomolecular Resource Center Mass Spectrometry Facility, the UCSF Core Facility for Genomics and Proteomics, the Center for Bioinformatics and Molecular Biostatistics, and the Bay Area Screening Center.

UCSF has a NIH T32 training grant (first funded in 1976) that provides salary support during the research portion of the fellowship program. Many fellows have also completed successfully for extramural funding from outsides sources such as the NIH, National Kidney Foundation (NKF), the American Heart Association (AHA) and others.

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