Basic and Translational

There are extensive opportunities for training in basic research within the Nephrology Division at UCSF. Didactic and lab-based learning are integrated into individualized training, tailored to the interests and goals of each Fellow. Most Fellows focus on one of five major themes:

  1. KidneyRenal tubule and ion transport physiology and cell biology;
  2. Renal immunology;
  3. Human genetics in Nephrology;
  4. Renal injury, metabolism, and fibrosis;
  5. Renal development and stem cell biology.

Beginning in 2012, we have launched a new initiative "Molecular Medicine in Nephrology” which provides selected bench-research physician-scientist fellows $40,000 funding to support their research.

The core of our training is extensive hands-on experience in the laboratory of one of our internationally renowned training faculty. With guidance and input from the Division Research Training Committee, Fellows are encouraged to choose a mentor whose research excites them, and fits best with their career goals.

Core training faculty include:

  • Marcus Delling, PhD, Assistant Professor and Chair, Physiology 
  • Michael Grabe, PhD, Associate Professor Cardiovascular Research Institute Department of Pharmaceutical Chemistry (molecular mechanisms of ion transporter function)
  • Lily Y. Jan, PhD, Professor of Physiology and Biochemistry and Molecular Biology (Voltage regulated K channels)
  • David H. Lovett, MD, Professor of Medicine (renal injury and fibrosis)
  • Keith E. Mostov, MD, PhD, Professor of Anatomy, Biochemistry and Molecular Biology (tubule cell biology and development)
  • David Pearce, MD, Professor of Medicine and Cellular and Molecular Pharmacology (Renal tubule and ion transport physiology and cell biology)
  • Jeremy F. Reiter, MD, PhD, Associate Professor of Biochemistry and Biophysics (Pathogenesis of polycystic kidney disease)
  • Shuvo Roy, PhD, Professor of Bioengineering and Therapeutic Sciences (Bioengineering with development of artificial kidney)
  • Dean Sheppard, MD, Professor of Medicine, Chief of the Division of Pulmonary, Critical Care, Allergy and Sleep
  • Alan S. Verkman, MD, PhD, Professor of Medicine (Nephrology) and Physiology (Renal tubule and ion transport physiology and cell biology)

Coursework for Basic Research Fellows:

Coursework for basic research fellows is designed by the fellow in collaboration with his/her primary research mentor and the T32 Committee.  In addition to required course work for all research fellows (see: Didactic Instruction), fellows are strongly encouraged to take 1-2 courses relevant to their research area.   Examples include:

Immunology

Genetics

Cell Biology   BMS 260

Developmental and Stem Cell Biology