Basic and Translational
There are extensive opportunities for training in basic research within the Nephrology Division at UCSF. Didactic and lab-based learning are integrated into individualized training, tailored to the interests and goals of each Fellow. Most Fellows focus on one of five major themes:
Renal tubule and ion transport physiology and cell biology;- Renal immunology;
- Human genetics in Nephrology;
- Renal injury, metabolism, and fibrosis;
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Renal development and stem cell biology.
Beginning in 2012, we have launched a new initiative "Molecular Medicine in Nephrology” which provides selected bench-research physician-scientist fellows $40,000 funding to support their research.
The core of our training is extensive hands-on experience in the laboratory of one of our internationally renowned training faculty. With guidance and input from the Division Research Training Committee, Fellows are encouraged to choose a mentor whose research excites them, and fits best with their career goals.
Core training faculty include:
- Onur Cil, MD, PhD, Assistant Professor (hyperoxaluria and nephrolithiasis)
- Marcus Delling, PhD, Assistant Professor (cilia and polycystic kidney disease)
- Michael Grabe, PhD, Professor, Cardiovascular Research Institute Department of Pharmaceutical Chemistry (molecular mechanisms of ion transporter function)
- Lily Y. Jan, PhD, Professor of Physiology and Biochemistry and Molecular Biology (Voltage regulated K channels)
- David Pearce, MD, Professor of Medicine and Cellular and Molecular Pharmacology (Renal tubule and ion transport physiology and cell biology)
- Jeremy F. Reiter, MD, PhD, Professor & Chair, Department of Biochemistry and Biophysics (pathogenesis of polycystic kidney disease)
- Shuvo Roy, PhD, Professor of Bioengineering and Therapeutic Sciences (Bioengineering with development of artificial kidney)
- Julie Saba, MD, PhD, Professor of Pediatrics (sphingolipid and nephrotic syndrome)
- Dean Sheppard, MD, Professor of Medicine, Chief of the Division of Pulmonary, Critical Care, Allergy and Sleep (integrins and renal fibrosis and failure)
- Alan S. Verkman, MD, PhD, Professor of Medicine (Nephrology) and Physiology (Renal tubule and ion transport physiology and cell biology)
Coursework for Basic Research Fellows:
Coursework for basic research fellows is designed by the fellow in collaboration with his/her primary research mentor and the T32 Committee. In addition to required course work for all research fellows (see: Didactic Instruction), fellows are strongly encouraged to take 1-2 courses relevant to their research area. Examples include: